MPA TECHNICAL DEVICES

MPA Srl is an Italian company that manufactures top quality special parts and pre-assembled units for the pharmaceutical, hospital, nautical, cosmetic and food sectors.

MATERIALS PROCESSED

MPA manufactures mechanical components and special parts using the following materials: titanium, stainless steel (AISI 316L-AISI 304-AISI 303), aluminium and its alloys, non-ferrous materials such as brass and bronze, plastic materials (delrin, arnite, polyethylene, peek, etc.) and special steel.

EXPERIENCE AND INNOVATION

Established in 1998 by Massimo Paradisi and his wife Antonella Carriero, over the years MPA has become a workshop outfitted with technological equipment. It carries out its activities in two industrial sheds, each one having a surface area of 700 sq.m.: one for the manufacturing of items destined to the pharmaceutical/cosmetic, hospital and food sectors, the other for manufacturing and assembly of products for the nautical sector.
The experience gained over the years has enabled the company to manufacture top quality special parts and pre-assembled units, specializing in the pharmaceutical, hospital, nautical, cosmetic and food sectors.

ITALIAN QUALITY

– long-standing experience in the sector
– organizational skills of our technical team
– innovative equipment and machinery
– skilled manpower
– use of choice raw materials
– passion for and commitment to our work
These are the aspects that mark out the quality of the services offered by MPA Srl, an Italian company that processes titanium, stainless steel, aluminium, brass, delrin, arnite, polyethylene and peek.

 

 

1) Filling Needles

  • Flat Tipped Needle

 

  • Scoop Tipped Needles

 

 

 

  • Basket Tipped Needles

 

 

 

  • Spherical Tipped Needles

 

 

 

 

  • PEEK/PTFE

 

2) Dosing Pumps

  • Stainless Steel Pumps

 

  • Ceramic or Titanium Pumps

 

 

  • Rotary Pumps

 

 

  • CIP / SIP Pumps

 

 

MORE THAN CLEANING.

Ultrasonic cleaners from the USC series by Adamus are efficient and functional devices that, owing to their high efficiency, accuracy, simple operation and quick work effects, are widely used in all industries and sectors.
The USC series cleaners handle every kind of dirt, even in hard-to-reach places.

 

Advantages of Ultrasonic Cleaner

  • They reduce cleaning time by up to 90%,
  • They require minimal operation control,
  • They are easy to install,
  • They do not require maintenance,
  • They do not cause any damage to the cleaned surfaces.

Ultrasonic cleaning make it possible to get perfectly clean items in less time than cleaning with conventional methods, such as manual or spray cleaning.

Ultrasound effectively removes impurities such as grinding and polishing pastes, abrasive, chips and filings, greases and cooling emulsions. The phenomenon of cavitation generated by ultrasound has a very intense effect which provides excellent results. Despite the strong impact, cleaning with ultrasonic cleaners does not cause any damage to the surface of the cleaned elements.

 

CATALOGE :

https://www.adamus.com.pl/index.php?option=com_edocman&task=document.download&id=23

 

 Ultrasonic Cleaner Series by Adamus

All Ultrasonic Cleaner series models are made of stainless steel, which guarantees resistance to corrosion and mechanical damage. Adamus cleaners are very well suited for professional use. They are characterised by the use of solid materials, careful craftsmanship with attention to detail, as well as easy operation. Most Ultrasonic Cleaner models are equipped with a drain tap that facilitates cleaning of the ultrasonic cleaner and emptying the tank.

 

 

 

Ultrasonic Cleaner

  • 4-step operation,
  • Heating range from 20 to 80 °C,
  • Thermostatic control,
  • LED display for set and current temperature,
  • Optical signal in case of temperature excess,
  • Clock for counting the working time or continuous work,
  • Continuous oscillation of the SweepTec ultrasonic wave,
  • DEGAS function: setting of pulsating sound for removing unwanted air bubbles displayed on the LCD panel,
  • Stainless steel housing protected against splashing,
  • The highest possible safety class: IP 33.

Even greater efficiency, owing to the DEGAS function

The DEGAS function removes air, including carbon dioxide from liquids, which causes the formation of more cavitation bubbles. The DEGAS function increases cleaning efficiency by over 30%.

 Even faster cleaning, owing to SweepTec technology

The SweepTec function ensures that ultrasound generators work at different frequencies, which results in even distribution of ultrasonic waves, and thus faster removal of dirt from the surface of the cleaned elements.

 Advantages of ultrasonic cleaning

  • Longer life of the cleaned elements, owing to the gentle and accurate operation of the ultrasonic cleaners
  • Fast cleaning process time
  • Economical use of water, chemicals and electricity
  • It is not possible to damage the cleaned elements and their surfaces
  • Excellent cleaning quality even in hard-to-reach places

How does an ultrasonic cleaner work?

A generator is installed in each sonic cleaner which emits ultrasonic waves. The waves move in the tank, causing alternating low and high pressure zones.

During the low pressure phase, microscopic, pulsating bubbles are formed, which first grow and then implode (collapse).

Implanting bubbles cause a shock microwave, which breaks the bonds between the dirt and the surface and reaches every gap, cavity, nook.

 Possibilities of using ultrasonic cleaners

Ultrasonic cleaners are used to clean surfaces made of metals and their alloys, plastics, glass, etc. Sonic cleaners are a great solution for cleaning heavily soiled as well as delicate items.

 

 

 

 Industry

  • Cleaning before powder painting, galvanizing (degreasing),
  • Cleaning, degreasing after hardening,
  • Cleaning after pressing,
  • Cleaning of parts from serial production after machining,
  • Cleaning of transport containers,
  • Cleaning of components,
  • Cleaning of filters,
  • Cleaning after polishing,
  • Cleaning of radiators,
  • Cleaning of forms,
  • Cleaning of castings.

 Regeneration

  • Cleaning of engine components,
  • Cleaning of gearbox components,
  • Cleaning of turbine components,
  • Cleaning of injection pump components,
  • Cleaning of injection elements,
  • Cleaning of rims and wheels with a tire.

 Laboratories, hospitals, dentistry, prosthetics

  • Cleaning of medical and laboratory tools (cuvettes, pipettes, bioanalyzers),
  • Degassing of liquids,
  • Cleaning of dentures,
  • Cleaning of dental instruments,
  • Cleaning of surgical instruments (endoscopes, gastroscopes, etc.).

 Jewelry, watchmaking, numismatics

  • Removing polishing paste and casting remains from products,
  • For cleaning soiled products,
  • Regeneration of components.

Punches and Dies

Punches and dies as a key element of the tablet formulation process. They are responsible for the final appearance and shape of the tablets manufactured, so they must be designed and manufactured with great accuracy and care. During operation, tools are exposed to significant static and dynamic forces. They often press abrasive or corrosive powders, which requires the use of high-quality steels, appropriately selected heat treatment, often coating with special coatings to prevent rapid tool wear or tablet sticking, or the use of special materials such as carbides.

Some applications (e.g. household chemicals or effervescent tablets) require the use of plastic inserts, such as Teflon or vulkollan, which further protect the pressing section and are a consumable component that can be replaced. ADAMUS S.A. designs and manufactures punches and dies for tablet presses of all types, according to EU (ISO), IPT (TSM) or specific tablet press manufacturers’ standards, according to customer needs. Our range includes tools for the manufacture of round and shaped tablets, monoblock and foldable, single- and multi-tip tools.

The tools can be supplied in special plastic boxes suitable for later storage. Each batch shipped is accompanied by a measurement record covering 100% of the tools delivered.

 

 

Tooling for exotic shaped tablets

With the appropriate design software and the manufacture based on digitally controlled machines, we also provide punches and dies with shapes more complex than those normally used in the pharmaceutical industry.

The only limitation to the variety of these shapes is the strength of the tools and the technological limitations of the tablet formation process. When developing new tablet shapes and forms, we remain open to collaboration, both with the marketing and R&D departments of our customers. The design of 2D and 3D tablets by an experienced team of engineers always takes into account the individual needs and expectations of our customers. Also with them in mind, our proprietary TabGen programme was developed, enabling buyers of products to verify their designs before starting the manufacturing process.

 

 

 

Multi-tip Punch and Dies

 

Multi-tip tooling applied by ADAMUS S.A. is a cost effective way to significantly increase the capacity of produced tablets without investing in the new tablet presses by reducing:

  • labour costs
  • maintenance costs
  • investment costs
  • energy costs

Multi-tipped tooling is available in two different configurations:

  • assembly construction – composite
  • solid construction – monoblock

The choice between those two options depends on the application, customer requirements, internal cleaning procedures and technical feasibility (the tablet dimensions and number of tips).

By using multi-tipped tooling the number of tablets produced per one turret revolution should be theoretically the multiple of the number of tips in the punch. However, due to the slightly lower turret speed connected with the necessity of the filling of more die holes, the real capacity can sometimes be lower. Depending on the product characteristic the measured capacity increase can vary but the mean values are ca. 1.5 for double-tiptooling, 2.8 for four-tip tooling and 4.5 for six-tip tooling

 

 

 

 

Special Tools

ADAMUS S.A. offers a wide variety of solutions used with regard to special client requirements. This enables us to manufacture top quality special tools.

  • punches with rotating heads
  • tools made of sintered carbides or tool with ceramic inserts
  • large-size tooling
  • tools for special tablets with holes (eg. catalysts)

 

Special Steels

The main requirements for steels used in the manufacturing of compression tooling are the wear resistance, good resistance to chipping, high compressive strength, good through hardening properties, high hardness after high temperature tempering and good stability in hardening.
ADAMUS S.A. uses steel grades which fulfill those requirements and purchase them only from world leading steel producers.
Besides the standard steel grades used by all compression tooling suppliers, ADAMUS S.A. offers a series of different specialty steels which can solve the tableting problems with abrasive, sticky and corrosive products as well as products which requires the higher compression forces than recommended due to the tablet size and dimensions. Such steels with the combination of different coatings, the right surface finish and very narrow dimensional tolerances make the tooling supplied by ADAMUS S.A. one of the best in the world.

 

 

Punch Coating

ADAMUS S.A. is constantly looking for innovative solutions to improve the degree of hardness of the surfaces of tools used in the manufacturing process using substances with different properties. Higher abrasion resistance, reduced coefficient of friction, minimised tendency to tool seizure, and increased corrosion resistance and anti-adhesion properties that eliminate sticking, are the result of our continuous research and development of tool coatings, the quality and durability of which are crucial for our customers.

 

 

 

Tablet designing

 

Various shapes

The company’s rich experience enables it to design tablets of various shapes with different engravings or logos, whilst taking into consideration the maximum durability of the tools used in manufacturing or the final layout of tablets (coating). The first stage of the design process includes the preparation of the tablet image.

Tablet or tool designs

Adamus S.A. is capable of preparing such an image following clients’ instructions or basing it on submitted tablet or tool designs. Furthermore, it is possible to calculate the mass of tablets of a certain shape or a change with the maintenance of the volume. Upon a client’s wish, 3-dimensional visualisations of the designed tablets are prepared.

 

Automatic Polishing Machines Pharma P&D

Pharma P&D series automatic polishers are an efficient and state-of-the-art solution for optimising the polishing process and maintaining compression tooling. The machines are designed to polish the largest number of punches and dies in the shortest possible time, while ensuring the highest quality and accuracy.

Pharma P&D polishers have been designed in line with the latest engineering standards. Made of stainless steel, with a simple design and intuitive control panel, they are easy to operate and do not require high-level qualifications.

 

Advantages of Pharma P&D polishing machines

  • Polishing time is 90% shorter compared to the manual polishing process.
  • Simple stainless steel design for easy maintenance.
  • A simple and intuitive operating system that does not require high-level qualifications.
  • Maximum efficient polishing of punches and dies ensures a quick return on investment.
  • Uniform, highest polishing quality for punches and dies regardless of the exotic shape, engraving size or opening size in the die.

 

Highlights of Pharma P&D polishing machines

Pharma P&D automatic polishing process allows to obtain the highest quality surfaces of polished compression tooling, thus extending their lifespan and preventing the most common problems with punches, such as bonding, lining or breaking tablets.

 

 

Easy
to operate

With the intuitive menu, the user can easily enter precise polishing parameters such as:

  • total machine operating time,
  • rotation times,
  • rotation speed of the polishing head.

Efficient
safety system

An automatic sensor precisely controls the position and engagement of the granulate container while an emergency button immediately stops the machine operation when required, thus protecting the punches at each polishing stage.

Highest
precision polishing

Dedicated holders allow the polishing medium to reach every part of polished compression tooling.

Punches polished
in just 30 minutes!

Depending on the wear of the punches, the polishing cycle lasts between 30 and 40 minutes.

Regular polishing ensures

 

 

  • Extends the life-time of punches and dies.
  • Provides an ideal surface of tooling, which reduces the amount of production waste.
  • Reduces most common problems in the tableting process and downtime risks.
  • Minimizes the risk of damaging the compression tooling

 

 

 

High performance

 

Holders have been designed to fit a whole set of upper and lower punches. Depending on the number of holders, P&D polishing machines allow up to 80 EU 19” (B) punches and 60 EU1” (D) punches to be polished in one cycle.

 

 

 

 

 

 

Compact design of Pharma P&D polishers

Pharma P&D series of automatic polishers comes in a simple design and is made of stainless steel to ensure long-term durability and allow contact with products of the pharmaceutical and food processing industries. The control cabinet and wiring are integrated into the device frame to optimise footprint.

 

TPR tablet coater

Standard drum tablet coater. Coating from 40% to 100%. Perforated pan technology allows automatic adjustment of flow, avoiding dampness, saving coating and optimising processing time. Built-in wall supports sustainability.

Batch size from 3.5 L to 900 L

 

Perforated coating pan for tablets and pellets

  • In-wall design concept
  • Built in AISI 316L, surfaces in contact with the product are mirror polished with roughness Ra <0.5
  • PLC + Intuitive HMI SIEMENS® for machine control in manual and automatic mode
  • Detachable deflectors
  • Central transmission with direct coupling
  • Schlick spray nozzles
  • All speed adjustments by frequency inverter
  • Central nozzle arm
  • WIP accessories for automatic cleaning
  • Spraying control by flow meter
  • Air control adjustments fully automatic
  • Automatic valves to isolate the process (GMP requirement)
  • Sight glass + LED illumination into the drum
  • Peristaltic pump (Watson Marlow) for coating suspension dosage
  • Remote connection

 

 Key Features

 

 

Functionalities

 

 

Machine Layout

 

 

 

Technical Data

 

Tablet Coaters Capacity​ (l) Dimensions (mm)
min. max. A B C D E
TPR i5-10 3.5 15 1,620 1,885 1,575 685 890
TPR i50 7.5 75 2,030 2,045 2,517 1,213 1,304
TPR 100 60 150 3,210 2,254 2,838 1,300 1,538
TPR 150 90 225 3,210 2,254 3,140 1,465 1,675
TPR 200 120 300 3,210 2,321 3,413 1,615 1,798
TPR 300 180 450 3,510 2,542 3,975 1,845 2,130
TPR 400 240 600 3,510 2,785 4,628 2,105 2,523
TPR 500 300 750 3,840 3,050 5,390 2,400 2,990
TPR 600 360 900 3,840 3,340 6,275 2,730 3,545

 

DATASHEET :

https://www.romaco.com/files/website/03_Products/03_Tecpharm/TP-R-Standard/04_Technical-Data/Files/Romaco_DB_Tecpharm_Coater_Std-EN.pdf

TPR Optima Tablet Coater

Fully automatic perforated coating pan without mechanical adjustments for film coating of tablets and pellets suitable for aqueous and organic coatings.

Performance: 7.5 L to 900 L

 

Smarter Tablet Coating – true 10% to 100% Fully automatic without mechanical adjustments.

  • Batch size range from 10% to 100% in a single drum
  • Fully automatic parameter setting
  • Automatic extension system for spray arm in relation to distance and angle
  • Automatic adjustment of the spray arm by sonar depending on the level of charge
  • Automatic regulation of air flow and path according to tablet or product load for a perfect coating performance
  • In-wall design concept
  • Built AISI 316L, with surfaces in contact with the product mirror polished with roughness Ra<0.5
  • Intuitive HMI with manual and automatic modes
  • Detachable deflectors
  • Central transmission with direct coupling
  • Schlick spray nozzles
  • All speed adjustments by frequency inverter
  • Remote connection as standard feature

 

Key Features

 

The OPTIMA Tablet Coater is a film coating machine based on perforated pan technology.

 

Its high technology allows an automatic adjustment control of the flow, avoiding the damp, saving coating and optimizing the process time.

 

 

Functionalities

 

 

Machine Layout

 

 

Technical Data

 

Tablet Coaters Capacity​ (l) Dimensions (mm)
Model min. max. A B C D E
TPR 50 Optima 7.5 75 3,210 2,254 2,799 1,276 1,510
TPR 100 Optima 15 150 3,210 2,260 2,799 1,276 1,538
TPR 200 Optima 30 300 3,210 2,321 3,413 1,615 1,798
TPR 300 Optima 45 450 3,510 2,542 3,975 1,845 2,130
TPR 400 Optima 60 600 3,710 2,785 4,154 1,937 2,217
TPR 500 Optima 75 750 3,840 3,050 4,306 1,953 2,323
TPR 600 Optima 90 900 3,840 3,340 6,275 2,730 3,545

 

DATASHEET :

https://www.romaco.com/files/website/03_Products/03_Tecpharm/TP-R-Optima/04_Technical-Data/Files/Romaco_Tecpharm_Optima_Coater_23.pdf

TPR Lab tablet coater

Perforated pan technology for small batches and simple formulations for tablets and pellets.

Performance: 0.75 to 3 L

 

 

Advanced coating technology in a pilot scale

  1. Ideal technology for product development that allows easy change to a pilot scale and provides useful information for industrial batches.
  2. The standard equipment is suitable to work with drums from 0.5 to 1 kg and 1 kg to 2 kg.
  3. Special drum execution is available to produce small batches for coating pellets.
  4. Spray ratio
  5. Inlet airflow
  6. Exhaust airflow
  7. Inlet and exit air temperature
  8. Tablet temperature during the process
  9. Turning speed of the pan drum

 

Key Features

 

 

 

Functionalities

 

 

 

Machine Layout

 

 

 

Technical Data

 

Tablet Coaters Capacity​ (l) Dimensions (mm)
Model min. max. A B C
TPR LAB Drum 1 0.75 1.5 1,290 1,760 800
TPR LAB Drum 2 1.5 3 1,290 1,760 800

 

 

DATASHEET :

https://www.romaco.com/files/website/03_Products/03_Tecpharm/TP-R-Lab/04_Technical-Data/Files/Romaco_Tecpharm_Coater_Lab_ENG_01.pdf

 

Romaco Tecpharm Optional and Peripheral equipment

Romaco Tecpharm offers a complete range of peripherals and optionals that allow the best performance of its equipment. These peripherals enable the production process to be further optimised and aligned to each customer’s specific requirements.

 

 

Optional and peripheral equipment

Exhaust air treatment [AHU o Dust collector]

  1. Primary filtration stage with powder collection in container/s
  • Cleaning filters by blowing system
  • Anti-explosion panel and shock valve
  • HEPA 13 absolute filtration
  • △P monitoring during the process
  1. Inlet air handling unit (AHU)
  • Prefiltration stage G4 and F9
  • Dehumidification unit
  • Heating unit
  • HEPA 13 absolute filtration
  • △P monitoring during the process
  1. Central WIP unit
  • Cleaning fluids preparation skid
  • Heat-insulated tank
  • Plate heat exchanger
  • Detergent tanks with dosing pumps
  • Drive pump
  1. Switch cabinet and controlling unit
  • Switch cabinet
  • Pneumatic integrated cabinet
  • UPS
  • HMI
  • Backup PC

 

Optionals

  • Automatic tablet unloading system
  • Nozzle blockage detection system with automatic self-cleaning
  • Desiccant wheel system for extra dehumidification
  • Heating unit with steam, oil or electric resistances
  • Coating suspension preparation tank (configurable)
  • Containment execution
  • Automatic sampling group
  • Central WIP unit, plate/tubular heating unit
  • Electropolish
  • 21 CFR part 11
  • ATEX rated

Unity 600 blister packaging line

Rotary sealing blister machine – Continuous motion cartoner – 2 tracks crosswise – Quick change over

600 blisters/min – up to 90 × 145 mm blister size. Up to 350 cartons/min

 

USPs

  • OEE (operational efficiency) optimized
  • Modular line concept, ready for connection to different track & trace systems
  • Good accessibility at the front with balcony design
  • New transfer system decreases energy costs
  • Simple settings and light-weight format parts
  • Low total cost of ownership (TCO)
  • Integrated service display for maintenance calibration
  • Possibility to pack sustainable packages like blister

 

Key Features

 

 

Functionalities

 

 

Machine Layout

 

 

Technical Data

 

Unity 600
Maximum output (blister/minute) 600
Maximum forming area (mm) 240 × 294
Maximum forming depth (mm) 12
Maximum output (cartons/minute), min. – max. 10–350
Carton dimensions (mm), A × B × C, min. – max. 35 × 15 × 65 to 95 × 100 × 157
Blister dimensions (mm), min. – max.​ 30 × 3 × 60 to 90 × 12 × 145

 

 

DATASHEET :

https://www.romaco.com/files/website/03_Products/04_Noack/Unity-600/04_Technical-Data/Files/Romaco_DB_Noack_new_Unity600-EN.pdf

Unity 500 blister packaging line

Rotary sealing blister machine – Continuous motion cartoner – up to 5 tracks lengthwise – Quick change over

500 blisters/min – up to 90 × 145 mm blister size. Up to 400 cartons/min

 

USPs

  • OEE (operational efficiency) optimized
  • Integrated turnkey concept
  • Automated processes with no manual adjustments
  • CO2 neutral manufactured and low CO2 emission per blister
  • Prepared for spatial separation of the primary and secondary packaging
  • Run-in times to almost Zero
  • First filling of the transfer magazine can be automated

 

Key Feature

 

 

Functionalities

 

 

Machine Layout

 

 

Technical Data

 

Unity 500
Maximum output (blister/minute) 500
Maximum forming area (mm) 190 × 204
Maximum forming depth (mm) 12
Maximum output (cartons/minute), min. – max. 10–400
Carton dimensions (mm), A × B × C, min. – max. 20 × 15 × 65 to 120 × 90 × 210
Blister dimensions (mm), min. – max.​ 30 × 3 × 60 to 90 × 12 × 145

 

DATASHEET :

https://www.romaco.com/files/website/03_Products/04_Noack/Unity-500/04_Technical-Data/Files/Romaco_DB_Noack_Unity500-EN.pdf

 

 

Unity 300 blister packaging line

Rotary sealing blister machine with continuous motion cartoner in single track crosswise operation. Quick change over – 3 years warranty.

300 blisters/min – up to 100 × 150 mm blister size. Ready to perform!

 

USPs

  • OEE (operational efficiency) optimized
  • Extremely low operational cost
  • CO2 neutral manufactured and low CO2 emission per blister
  • Ready for connection to various track & trace systems
  • Fully integrated Monoblock with small footprint of 8.5 m total and only 4 m in clean room
  • Optional paper blister production module
  • Free return recycle guarantee for equipment at the end of the service life
  • Versatile – integration of ROMACO PPT (Promatic track & trace) system, any other third party & trace system

 

Key Features

 

 

 

Functionalities

 

 

Machine Layout

 

 

 

Technical Data

 

Unity 300​
Maximum output (blister/minute) 300
Maximum forming area (mm) 150 × 190
Maximum forming depth (mm) 12
Maximum output (cartons/minute), min. – max. 10–300
Carton dimensions (mm), A × B × C, min. – max. 35 × 15 × 65 to 105 × 100 × 160
Blister dimensions (mm), min. – max.​ 30 × 3 × 60 to 100 × 12 × 150

 

DATASHEET :

https://www.romaco.com/files/website/03_Products/04_Noack/Unity-300/04_Technical-Data/Files/Romaco_DB_Noack_Unity300-EN.pdf

 

Unity 200 blister packaging line

Platen sealing blister machine – Continuous or intermittent motion cartoner – lengthwise operation – quick change over

200 blisters/min – up to 115 × 155 mm blister size. Up to 200 cartons/min

 

USPs

  • OEE (operational efficiency) optimized
  • No need to change parts on transfer unit
  • Easy handling and application flexibility
  • Very compact Monoblock design
  • Flexibility for high blister counts in cartons
  • Balcony design with optional 21 CFR part 11 compliance
  • Double pick and single release of blisters with delta robot

 

 

Key Features

 

 

 

Functionalities

 

 

Machine Layout

 

 

Technical Data

 

Unity 200​
Maximum output (blister/minute) 200
Maximum forming area (mm) 138 × 155
Maximum forming depth (mm) 12 (optional 25)
Maximum output (cartons/minute), min. – max. 10–200
Carton dimensions (mm), A × B × C, min. – max. 20 × 15 × 60 to 120 × 80 (opt. 95) × 200
Blister dimensions (mm), min. – max.​ 52 × 28 × 3 to 115 × 155 × 12

Datasheet :

https://www.romaco.com/files/user_upload/Romaco_DB_Noack_Unity200-EN.pdf

NBP 950 blister packaging machine

Rotary sealing blister machine – 5 tracks lengthwise operation – Quick change over

500 blisters/min – up to 162 × 204 mm blister size

 

USPs

  • Designed for small to medium batch sizes
  • Full compatibility of format parts with the Noack 921
  • Easy line integration
  • Advanced level of automation
  • Quick-feed for optimized cleaning
  • Choice of dedicated optical monitoring systems
  • OPC UA interface for production data acquisition

 

Key Features

 

 

Functionalities

 

 

Machine Layout

 

 

Technical Data

 

  NBP 950
Maximum output (blister/minute) 500
Maximum forming area (mm) 190 × 204
Maximum forming depth (mm) 12
Blister dimensions (mm), min. – max.​ 20 × 3 × 35 to 162 × 12 × 204

NBL 400 2.0 blister packaging line

Rotary sealing blister machine – continuous motion cartoner – up to 5 tracks lengthwise – quick change-over – 4 months to delivery

400 blisters/min – up to 162 × 204 mm blister size

 

USPs

  • Excellent price-performance ratio
  • Format part compatible with Noack N 921 and NBP 950
  • Flexible Line configuration
  • Fast deliver
  • Robust 4-column design of forming station for perfect forming forming of all kinds of materials (Alu/Aku – Alcar – COC – PVC/PDVC – …)
  • Ideal for contract packing companies and pharmaceutical start-ups

 

Key Features

 

 

 

Functionalities

 

 

 

Machine Layout

 

 

Technical Data

 

  NBL 400
Maximum output (blister/minute) 400
Maximum forming area (mm) 190 × 204
Maximum forming depth (mm) 12
Maximum output (cartons/minute), min. – max. 10–200
Carton dimensions (mm), A × B × C, min. – max. 35 × 15 × 65 to 105 × 100 × 160
Blister dimensions (mm), min. – max.​ 35 × 3 × 20 to 162 × 12 × 204

N 760 blister packaging machine

Platen sealing blister machine – 4 tracks lengthwise/crosswise operation – short retooling times

200 blisters/min – up to 136 × 154 mm blister size

 

USPs

  • Optimal entry level
  • All common sealable foils can be processed
  • Robust and reliable
  • Easy to operate
  • Small footprint
  • Child-resistant packs, paperback lidding foil, Alu cold form
  • Quick change-over due to innovate servo technology

 

 

Key Features

 

 

 

Functionalities

 

 

Machine Layout

 

 

Technical Data

 

N 760​
Maximum output (blister/minute) 200
Maximum forming area (mm) 155 × 138
Maximum forming depth (mm) 25
Blister dimensions (mm), min. – max.​ 28 × 3 × 54 to 136 × 12 × 154

 

 

DATASHEET:

https://www.romaco.com/files/website/03_Products/04_Noack/DPN-760/04_Technical-Data/Files/Romaco_DB_Noack_760-EN.pdf

N 623 high performance platen sealing machine

Platen sealing blister machine – up to 6 tracks crosswise/lengthwise operation – ideal for packing tablets, capsules, ampoules and syringes

420 blisters/min – up to 224 × 156 mm blister size

 

USPs

  • Robust and reliable
  • User friendly
  • Quick format changes and easy adjustment
  • Short change-over times
  • Die-cutting technology helps reduce waste
  • Upgrade options to increase productivity
  • cGMG compliant

 

Key Features

 

 

Functionalities

 

 

Machine Layout

 

 

 

Technical Data

 

N 623
Maximum output (blister/minute) 420
Maximum forming area (mm) 225 × 158
Maximum forming depth (mm) 25
Blister dimensions (mm), min. – max.​ 28 × 3 × 54 to 158 × 12 × 225

 

DATASHEET :

https://www.romaco.com/files/website/03_Products/04_Noack/N-623/04_Technical-Data/Files/Romaco_DB_Noack_623-EN.pdf

 

Oftalmica liquid filling machine

Sterile liquid filling and capping. The Oftalmica machine’s main application is filling and capping of ophthalmic products; additionally, it can easily handle nasal sprays and injectables (small formats).

Max. 12,000 bottle/hour

 

The art and science of ophthalmic filling

  • Minimized change-over parts and downtime due to wide adaptability range of transport system and machine stations
  • Dosing system designed according to ophthalmic production needs – capable to maintain high speed/max. output even with viscous and foamy liquids which need to be fed into bottles with small mouths
  • Machine designed for aseptic processing according to the latest Annex 1 of cGMP for the manufacturing of sterile medicinal products:
    • also suitable for injectable applications
    • turnkey solution with washer and tunnel available
  • Capping stations can handle all kinds of caps (Aptar, Nemera, Dropper + Screw cap, cannulas, spray pumps and so on)
  • All containers can be steadily run – from glass vials to lightweight plastic bottles

Key Features

 

 

Functionalities

 

 

 Machine Layout

 

Technical Data

 

OFTALMICA
Output – single dose (vials/hour)* 12,000 up to 15 ml filling volume
Vial dimensions, diameter range (mm) 16–32
Vial dimensions, height range (mm) 42–80
Filling range (ml)* 1–30
Installed power (kW) 35
Compressed air consumption (NL/min) 550
PLC standard Schneider
HMI B&R
*Depending on product and machine configuration

 

DATASHEET : https://www.romaco.com/files/website/03_Products/06_Macofar/Oftalmica/04_Technical-Data/Files/Romaco_DB_Macofar_Oftalmica-EN.pdf

 

Robotic powder/liquid filling machine for small batches

Robotic powder/liquid filling machine for small batches under isolation technology. The MicroRobot 50 can be configured for powder and/or liquid filling (combi filling) under isolation technology – even of high potency drugs and extremely difficult to fill powders. Size parts-free robots manage all operations and vials transfer.

Max. 3,000 vials/hour with minimum dosage: 20 mg / 0.5 ml

 

Innovation and value

  • Format-free robotic transport
  • Zero loss logic for high value products
  • Compact design
  • Filling, stoppering, and capping all in one machine
  • One single machine capable of handling both powder and liquid filling
  • Capable of handling oxygen-sensitive products due to a system to reduce oxygen level below 3 %

 

Key Features

 

 

Functionalities

 

Machine Layout

 

 

Technical Data

 

Output – single dose (vials/hour) 3,000
Vial dimensions diameter (mm), min. – max. 16–52
Vial dimensions height (mm), min. – max. 35–110
Minimum dose (mg), min. dosages can change according to the powder specific weight 20
Minimum dose liquid (ml), can vary depending on product’s characteristics 0.5
Installed power (kW), without L.F. 22
Compressed air (bar) 6
PLC standard SCHNEIDER
Machine dimensions (mm), L × W × H 3,950 × 1,700 × 3,000
Weight (kg) approx. 6,000
*Depending on product and machine configuration

 

DATASHEET :

https://www.romaco.com/files/website/03_Products/06_Macofar/MicroRobot-50/04_Technical-Data/Files/Romaco_DB_Macofar_MicroRobot-EN.pdf

MicroMaxX Series for sterile powder filling

High speed sterile powder filling and stoppering. Double powder dosing station machine with highly ergonomic supply of product components in aseptic environment. Vacuum-pressure technology, integrated check weighing system and rubber stoppering by means of pick and place with verification of cap presence are some of the key features of MicroMaxX Series.

Up to 24,000 vials/hour with a filling range (single shot per dosing disc) of 30 mg to 1,500 mg

 

Where versatility and fast production meet

  • Up to two different types of powders filled into the same vial
  • 100% in line check weighing with feedback to dosing system
  • Easy tool-free replacement of product contact parts from machine front side
  • Ergonomic handling of components
  • Compact footprint
  • Unique LEV design to minimize powder dispersion in the filling area
  • Suitable for oxygen-sensitive products due to system for reducing oxygen level below 3 %

 

Key Features

 

 

Functionalities

 

 

 

Machine Layout

 

 

Technical Data

 

MicroMaxX 18 MicroMaxX 24
Vials Diameter (mm), min. – max. 16–52 16–32 16–52 16–32
Vials Height (mm), min. – max. 35–110 35–75 35-110 35–75
Maximum output (vials/hour)*
Single dose per dosing disc, no C.W.
6,000 18,000 12,000 24,000
Maximum output (vials/hour)*
Single dose per dosing disc, 100 % C.W.
4,000 12,000 12,000 24,000
Dosing range (mg), min. – max.
Single shot per dosing disc, dosage can change in relation to powder specific weight
20–1,500
Discs Two single Two double
Dosing chambers per disc 12 12+12
Power consumption (kW), without L.F. – with L.F. 12.7 – 16.7
Compressed air for powder ejection (Nl/min), at 7 bar 120
*Depending on product and machine configuration

 

 

DATASHEET :

https://www.romaco.com/files/website/03_Products/06_Macofar/MICROMAXX-Series/04_Technical-Data/Files/Romaco_DB_Macofar_Micromaxx-EN.pdf

Micro Series for powder filling

Sterile powder filling and closing of glass vials. Available as monoblock configuration including powder filling, stoppering and capping up to 6,000 vials per hour, or as a pure filling and stoppering system up to 18,000 vials per hour. Micro series features vacuum-pressure dosing technology to accurately fill powder into glass vials. Machines can be equipped with check weighing unit, environmental controls and pre-loading of packaging materials to handle sterile productions at best.

Up to 18,000 vials/hour with a filling range of 50 mg to 1,500 mg

 

Compact, user-friendly solutions for your aseptic powder filling

  • Cost-effective solution
  • Compact design for minimum footprint in the cleanroom
  • Highly reliable vacuum pressure dosing system suitable for steady production and big batches
  • Two dual disc stations for double powder filling with statistical check weighing before and after each dosage available on demand
  • Exceptionally compact design available with alu capping included as option
  • Monoblock machine
  • Ideal application for high value powders due to special designed hopper
  • Easy to operate

Key Features

 

 

Functionalities

 

 

Machine Layout

 

 

 

Technical Data

MICRO 6 MICRO 9 MICRO 18 MICRO 9 2D MICRO 18 2D
Output – single dose (vials/hour) 5,000 9,000 18,000 9,000 18,000
Vial dimensions diameter (mm), min. – max. 16–52 20–52 16–52 20–52
Vial dimensions height (mm), min. – max. 35–110 40–110 35–110 40–110
Minimum dose (mg), min. dosages can change according to the powder specific weight 20 50 20 50
Maximum dose with single dose (mg), max. dosages can change according to the powder specific weight 1,500
Dosing disc One single One double Two single Two double
Dosing port per disc 12 12+12 12 & 12 12+12 & 12+12
Power consumption (kW), may vary depending on configuration 5.4
1.8 LAF
9
1.8 LAF
1.5 C.W.
Compressed air for powder ejection (l/min) 70 120
Vacuum pump (m3/h) 100
PLC standard SCHNEIDER
Net weight (kg), may vary depending on configuration 1,800 2,000 2,100 2,000 2,100
Gross weight (kg), may vary depending on configuration 2,100 2,300 2,400 2,300 2,400
*Depending on product and machine configuration

 

DATASHEET :

https://www.romaco.com/files/website/03_Products/06_Macofar/MICRO-Series/04_Technical-Data/Files/Romaco_DB_Macofar_Micro_6-EN.pdf

MACRO Series for powder filling and capping

Non-sterile powder filling and capping. High accuracy filling of non-free flowing powders and dry syrups into glass or plastic bottles. Closing unit can be customized to handle any type of cap.

Up to 8,000 bottles/hour

 

Reliable technology for precise powder filling in non-aseptic operations

  • Glass partition wall separating the closing station from the filling station to avoid particle contamination of the bottles
  • Individually configurable pistons and stainless steel wire mesh filters according to powder’s physical properties
  • Also available without the closing group
  • Multiple filling into one bottle to increase the dosing range available upon demad
  • No bottle no filling available upon demand

 

Key Features

 

Functionalities

 

 

Machine Layout

 

 

Technical Data

 

MACRO-D 5 MACRO-D 8
Format range diameter (mm), min. – max. 30–60
Format range height (mm), min. – max. 50–170
Mechanical production (pieces/hour), depending on vial stability, powder characteristics and installed options 5,000 8,000
Standard dosing range (cc), min. – max. (single shot) 6–90
Installed power (kW), only dosing 5
Installed power (kW), with closing unit 7
Compressed air consumption (Nl/min.) 200
Compressed air pressure (bar) 7
Net weight (kg) 1,700 1,950
Gross weight (kg) 2,200 2,700
*Depending on product and machine configuration

 

DATASHEET :

https://www.romaco.com/files/website/03_Products/06_Macofar/MACRO-Series/04_Technical-Data/Files/Romaco_DB_Macofar_Macro-EN.pdf

MACOFAR E liquid filling

Sterile liquid filling lines. MACOFAR E includes a series of washers, depyrogenation tunnels and liquid filling machines to configure the perfect aseptic liquid filling line for vials intended for injection.

Up to 24,000 vials/hour

 

Quality – budget – schedule on point

  • Sterile liquid filling turnkey solution up to external decontamination machine
  • Selection of preset configurations for sterile liquid filling matching the needs of the pharmaceutical industry
  • Cost-effective solution
  • 100 % tare/gross check weighing system with automatic filling adjustment
  • Zero loss logic end-of-batch procedure

 

Key Features

 

 

Functionalities

 

 

Machine Layout

 

 

Technical Data

 

 

Aseptic Liquid Filling
Maximum speed (vials/hour),
based on 10R-2ml filling volume
Washer – a (mm) Depyrogenation tunnel – b (mm) Filler – c (mm) Utilities (Power / Water / Compressed air)
6,000 MRW 12/2 – 2,840 MDT 422 – 3,620 MVF 100 – 3,850 Installed power 90 kW; 400 L/h 3 bar WFI; 30 Nmq/h 6 bar CA
12,000 MRW 12/4 – 2,840 MDT 622 – 3,820 MVF 200 – 4,300 Installed power 125 kW; 600 L/h 3 bar WFI; 45 Nmq/h 6 bar CA
24,000 MRW 20/5 – 3,260 MDT 944 – 4,550 MVF 400 – 5,400 Installed power 225 kW; 1200 L/h 3 bar WFI; 90 Nmq/h 6 bar CA

 

 

MAC Series for alu capping

Sterile alu capping of vials. MAC machines are designed for aseptic processes and top-quality sealing of vials.

Up to 24,000 vials/hour

 

aseptic process

  • Alu caps are sealed by moving the vials from below, ensuring the highest quality and preventing scratches or defects
  • Secure closing of vials thanks to dedicated idle blade and upper vial contrast, which is optionally equipped with loading cell to continuously monitor sealing force
  • Optimised machine layout to avoid contamination from aluminum particles potentially caused by the caps feeding bowl
  • Sealing force can be set via machine HMI

 

Key Features

 

 

Functionalities

 

 

Machine Layout

 

 

Technical Data

 

MAC 2 MAC 4
Vials Diameter (mm), min. – max. 16–35
Vials Height (mm), min. – max. 35–100
Maximum output (vials/hour)* 12,000 24,000
Closing heads 2 12
Motion Intermittent Continuous
Rated power (kW) 2.5
Weight (kg)* 800
PLC SCHNEIDER
*Depending on product and machine configuration

 

DATASHEET :

https://www.romaco.com/files/website/03_Products/06_Macofar/MAC-Series/04_Technical-Data/Files/Romaco_DB_Macofar_MAC-EN.pdf

LVI Series for liquid filling

Sterile and non-sterile liquid filling and capping. Compact versatility for complex products: LVI machines can be equipped with different types of liquid filling technologies and capping options. Suitable to handle a wide range of pharmaceutical liquid products. The machine can also be equipped with laminar flow and environmental controls for aseptic processes.

Up to 6,000 bottles/hour

 

Your little liquid filling all-rounder

  • Compact design
  • Exceptional versatility:
    • wide filling and format range
    • can handle injectable, ophthalmic, oral and nasal products
  • Multiple capping stations

 

Key Features

 

 

Functionalities

 

 

Machine layout

 

 

Technical Data

 

LVI 4 LVI 6
Mechanical output 4,000 6,000
Fill range (cc.) 1 – 500 1 – 100
Vial range diameter (mm) min. 16 – max. 75 min. 16 – max. 48
Vial range height (mm) min. 35 – max. 180
Rated Power (kW) 5
Compressed air (bar) 6
Dimensions (mm) 3,535 × 1,410 × 2,138
Net weight (kg) 1500
Air consumption (Nl/min.) 200
PLC SIEMENS
*Depending on product and machine configuration

 

DATASHEET :

https://www.romaco.com/files/website/03_Products/06_Macofar/LVI-Series/04_Technical-Data/Files/Romaco_DB_Macofar_LVI-EN.pdf

 

LF Series for liquid filling and capping

Efficient solution for filling of non-aseptic pharmaceutical and nutraceutical liquid products into a wide range of glass and plastic bottles. The machines can be equipped with up to three capping stations plus a straw/cannula feeding unit.

 

Up to 15,000 bottles/hour

 

High speed and versatility for non-aseptic liquid filling

  • From sugary, highly viscous products, such as syrups, to alcohol-based, low viscosity products, within the same machine configuration
  • Multiple caps handling – screw caps, child-proof caps, droppers, spray pumps, measuring caps and more
  • Reliable solution for continuous production of big batches

 

 

Key Features

 

 

Functionalities

 

 

Machine Layout

 

 

Technical Data

 

LF 150 LF 200 LF 250
Mechanical output (pieces/hour) 9,000 12,000 15,000
Fill range (cc.) 25 ÷ 450 5 ÷ 250 5 ÷ 70
Vial range diameter (mm) min. 25 – max. 80 min. 20 – max. 80 min. 20 – max. 38
Vial range height (mm) min. 40 – max. 180
Rated Power (kW) 12.6
Compressed air consumption (Nl/min.) 200
PLC SCHNEIDER
*Depending on product and machine configuration

DATASHEET :

https://www.romaco.com/files/website/03_Products/06_Macofar/LF-Series/04_Technical-Data/Files/Romaco_DB_Macofar_LF_Series-EN.pdf

CD Series for capsule filling

Easy to use and to clean. CD capsule fillers can successfully handle all kinds of powders and pellets in a very compact footprint.

Up to 40,000 capsules/hour

 

Reliable technology for continuous production

  • Powder dosing unit performing vertical movements without any kind of rotation
  • Dedicated dosing system for pellets, preserving product quality and integrity
  • Vacuum-assisted dozers
  • Double opening station ensuring that the highest number of capsules are opened, thus reducing empty capsules rejections

 

 

Key Features

 

 

Functionalities

 

 

Machine Layout

 

 

Technical Data

CD 40
Maximum output (capsules/hour) 40,000
Capsule size 00 – 0 – 1 – 2 – 3 – 4 – 5
Rated power (kW) 3.5
Machine compressed air (Nl/min)  150
Machine + CW compressed air (Nl/min) 350
Machine dimensions, approx. (W × H × L, mm) 980 × 1,510 × 2,080
Weight, approx. (kg) 1,200

 

DATASHEET :

https://www.romaco.com/files/website/03_Products/06_Macofar/CD-40/04_Technical-Data/Files/Romaco_DB_Macofar_CD_40-EN.pdf

SYNTHESIS 500 TT/TTH rotary tablet press

The fastest and most accurate rotary tablet press for tab-in-tab production and dry-coating.
30 to 50 press stations for max. 140,000 tablets/hour

 

Precise – fast – clean tablet compression

  • Easy set-up and core position control via camera system
  • Fast tab-in-tab production
  • Low cleaning effort due to few products contact parts
  • Minimal product loss
  • No cross-contamination due to effective separation between processing and maintenance area

 Key Features

 

 

Functionalities

 

Machine Layout

 

DATASHEE

https://www.romaco.com/files/website/03_Products/02_Kilian/SYN-500-TT/04_Technical-Data/Files/Romaco_DB_Kilian_SYN_500-EN.pdf

 

 

Technical Data

 

Machine configurations Tab-in-tab
Number of press stations 30 35 45 50
Tool type* (EU and TSM) D B B B
Die type D B BB BBS
Maximum tablet diameter (mm) 24 16 13 11
Maximum output TT version** (tablets/hour) 45,000 52,500 67,500 75,000
Maximum output TTH version** (tablets/hour) 84,000 98,000 126,000 140,000
Maximum die filling first layer(mm) 20 18
Maximum punch penetration second layer (mm) 9
Maximum compression force first layer (kN) 10
Maximum compression force second layer*** (kN) 100 80
Standard voltage (V), frequency (Hz) 400, 50/60
Compressed air (bar) 6
Weight (kg) 3,580

S 710 Prime rotary tablet press

Economic, double-sided rotary tablet press with high-end key features and an outstanding price-performance-ratio for high-volume production of mono- and bi-layer tablets.

51 to 85 press stations for max. 1,020,000 tablets/hour

 

Economic – fast – clean tablet compression

  • Compression force up to 100 kN
  • Tablet chute on a swivel arm
  • Simple, tool-free handling and fast cleaning
  • Separation between compaction and service area
  • Short maintenance time due to long lasting parts

 Key Features

 

 

Functionalities

 

 

Machine Layout

 

 

DATASHEET : https://www.romaco.com/files/website/03_Products/02_Kilian/S-710-Prime/04_Technical-Data/Files/Romaco_DB_Kilian_KTP_S_710_Prime-EN.pdf

 

Technical Data

 

* Special tools/formats available on request.

** The output depends on tablet size and compressed material.

*** Maximum punch load dependent on tablet design.

Technical Data

Machine configurations

Mono-layer; Bi-layer  
Number of press stations 51 51 63 77 85
Tool type* (EU and TSM) D KILIAN 28/41 B B B
Die type D D B BB BBS
Maximum tablet diameter (mm) 24 25 16 13 11
Maximum output Mono-layer** (tablets/hour)  550,000 550,000 753,000 924,000 1,020,000
Maximum output Bi-layer** (tablets/hour) 275,000 275,000 376,500 462,000 510,000
Maximum die filling (mm) 20 18
Maximum pre-compression force*** (kN) 100
Maximum main-compression force *** (kN) 100
Standard voltage (V), frequency (Hz) 400, 50/60
Compressed air (bar) 6
Weight (kg) 5,400

 

 

 

S 370 Prime rotary tablet press

Reliable, mid-sized mono-layer rotary tablet press for completely automatic production of budget sensitive pharmaceutical applications.

26 to 44 press stations for max. 330,000 tablets/hour

 

Modular compact flexible tablet compression

 

  • Compact designed machine with included electronic components – small footprint and light weight
  • Exchangeable die table
  • Fast set-up and easy operation due to the simple and user-friendly HMI control system
  • Ready-to-connect tablet check unit for automatic in-process control
  • Made in Germany

 

Key Features

 

 

 

Functionalities

 

 

Machine Layout

 

 

Technical Data

 

Machine configurations Mono-layer
Number of press stations 26 32 40 44
Tool type* (EU and TSM) D B B B
Die type D B BB BBS
Maximum tablet diameter (mm) 25 16 13 11
Maximum output** (tablets/hour) 156,000 240,000 270,000 330,000
Maximum die filling (mm) 20 16
Maximum pre-compression force*** (kN) 40
Maximum main-compression force *** (kN) 100
Standard voltage (V), frequency (Hz) 400, 50/60
Compressed air (bar) 6
Weight (kg) 1,925

 

DATASHEET:

https://www.romaco.com/files/website/03_Products/02_Kilian/S-370-Prime/04_Technical-Data/Files/Romaco_DB_Kilian_S_370_Prime-EN.pdf

S 250 SMART rotary tablet press

Economic, mid-sized, single-sided rotary tablet press for compression of any powder mixture.
26 to 44 press stations for max. 300,000 tablets/hour
SMART tablet compression
S = Simple handling
M = Modular packages
A = Automated operation
R = Robust & compact design
T = Turret exchange
• Minimal product loss
• Savings of valuable space in production due to interchangeable electrical cabinet

 

Key Features

 

 

Functionalities

 

 

Machine Layout

 

 

Technical Data

 

“>

Machine configurations Tradition; Classic
Number of press stations 26 32 40 44
Tool type* (EU and TSM) D B B B
Die type D B BB BBS
Maximum tablet diameter (mm) 25 16 13 11
Maximum output** (tablets/hour) 156,000 220,000 270,000 300,000
Maximum die filling (mm) 20 16
Maximum pre-compression force*** (kN) 40
Maximum main-compression force *** (kN) 100
Standard voltage (V), frequency (Hz) 400, 50/60
Compressed air (bar) 6
Weight (kg) 1,925

 

DATASHEET : https://www.romaco.com/files/website/03_Products/02_Kilian/S-250-SMART/04_Technical-Data/Files/Romaco_DB_Kilian_S250SMART-EN.pdf